albicans, increases in the concentration of Reynoutria elliptica extract led to significantly increased antimicrobial effects. In CFU and agar disk diffusion tests with C.
albicans was significantly higher than was that seen for the control group. Several experimental groups showed cell viability higher than 70%, and the antimicrobial activity toward both S. In addition, UV/VIS spectroscopy was used to determine the levels of flavonoid and polyphenol in experimental solutions. Fine particles of Reynoutria elliptica extract were used to probe for biocompatibility and antimicrobial activity toward these pathogens, and results were evaluated with an MTT (3-2,5 diphenyl tetrazolium bromide) assay, spectrophotometric growth inhibitory assay, the total number of colony-forming units (CFU), an agar disk diffusion test, and scanning electron microscopy (SEM). This study was conducted to determine whether nature-derived Reynoutria elliptica extracts exhibit biocompatibility and antimicrobial effects against oral pathogens such as Streptococcus mutans and Candida albicans.
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